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Coronavirus lockdown day 1 live updates | Madhya Pradesh statistics first dying, Karnataka sees 10 new situations India has 618 validated situations of COVID-19, of which 562 are lively, in accordance with statistics from the fitness Ministry and State governments. The dying toll stands at 13, with Tamil Nadu and Madhya Pradesh recording their first COVID-19 deaths.  Gujarat has reported its 2nd dying. COVID-19 | Interactive map of established cases in India amongst India’s immediate neighbours, China has registered over eighty,000 established instances so far, based on the WHO. Over three,000 americans have died due to the virus. In Pakistan, over 800 proven situations and six deaths were registered. The Hindu has brought out an e-e-book on essential COVID-19 suggestions, apart from overlaying the traits involving the coronavirus pandemic because it unfolded. listed here are answers from specialists to your queries concerning the virus, a list of State Helpline numbers, and a map of tested circumstances in India. the new 24/7 country wide helpline numbers are 1075 and 1800-112-545 and  011-23978046. email: ncov2019-at-gmail.com. The leading Minister has announced a WhatsApp helpdesk quantity:  9013151515. here are the newest updates:  eleven.25 p.m. | Tamil Nadu Tamil Nadu studies three greater situations Three more cases has been reported from Tamil Nadu. State fitness Minister C. Vijayabaskar tweeted that an 18-12 months-ancient man who was in contact with Tamil Nadu’s second patient, a Dubai-returned 63-yr-ancient man who lower back from Dubai and a 66-yr-old Man who was in contact with infected Thai nationals are among the many new instances. the brand new cases are isolation on the Rajiv Gandhi government widespread sanatorium, Chennai, Wallajah GH and IRT, Perundurai respectively.   10.45 p.m.| Telangana/A.P. Telangana, A.P. record two sparkling instances each Telangana and Andhra Pradesh have pronounced two new cases of coronavirus each. Of both A.P. circumstances, one has back from the U.S. and the different from Delhi. 10.40 p.m. | Rajasthan Two sparkling COVID-19 fine circumstances have been reported in Rajasthan. One each and every from Bhilwara and Jhunjhunu, taking the variety of coronavirus-contaminated patients in the State to 38. 10.20 p.m. | Gujarat second death pronounced in Gujarat a woman patient infected with Coronavirus has died in Ahmedabad civil hospital. here is the 2nd death in Gujarat. Tamil Nadu The second high quality COVID-19 patient in Tamil Nadu, who turned into present process remedy is convalescing smartly and will be discharged in two days. Punjab Two fresh circumstances mentioned in Punjab taking complete to 31 The Punjab executive on Wednesday issued a fresh set of directives to the police and civil administration to make sure that the individuals don’t seem to be inconvenienced all over the lockdown even because the State has stated two fresh cases of COVID-19. The State’s fitness department noted two new circumstances of COVID-19 had been stated in Punjab on March 25 taking the overall to 31. One patient is from the Hoshiarpur district is a detailed contact of a good case. The different patient is from Ludhiana and doesn’t have a shuttle history. The source of the affected person’s an infection is being recognized, it said.   eight.00 p.m. | Karnataka Karnataka sees 10 new circumstances on March 25, total rises to 51 Ten new circumstances of COVID-19 have been established in Karnataka on March 25 taking the total variety of cases to fifty one. despite the fact fitness Minister B. Sriramulu tweeted on March 25 morning that a girl from Gowribidanur who established effective after coming back from Mecca succumbed to the infection in Bowring and girl Curzon health facility at 1 a.m. on Wednesday, branch officials pointed out as she also had different co-morbidities, they had been anticipating all her different studies. The 51 situations include one dying and three humans who were discharged. Uttar Pradesh The COVID-19 fantastic situations in UP is now 38, with a sparkling case in Pilibhit, as per directorate of fitness functions. The affected person is a contact of a contemporary fantastic case, a girl who had travelled from Saudi Arabia. Election commission allows use of indelible ink to mark those quarantined The Election commission of India on Wednesday mentioned it had allowed the government to use indelible ink, which is always used to mark voters, to mark people ordered quarantine themselves at home in view of the “fabulous situations” because of the coronavirus (COVID-19) pandemic. In a letter to the Union fitness and family unit Welfare Ministry, the ECI wrote that it had taken the suo motu decision to permit the use of indelible ink with definite conditions. The ECI’s determination followed a couple of State governments the usage of distinctive stamps to mark people who had been ordered to quarantine at home after getting back from overseas.   6.40 p.m. | Indore M.P statistics first dying Madhya Pradesh recorded its first COVID-19 dying after a sixty five-year-ancient lady, at first from Ujjain, succumbed to the disorder in Indore on Wednesday. She was demonstrated high quality previous these days. Mamata Banerjee calls for ₹1,500 crore package from Centre to address coronavirus West Bengal Chief Minister Mamata Banerjee on Wednesday sought a ₹1,500 crore package from the Centre to help the State govt’s efforts to deal with the coronavirus (COVID-19) outbreak. chatting with journalists through video-convention from the State secretariat, Ms. Banerjee mentioned the Centre should still give a distinct package because the State is finding it complicated to do “every little thing” with its “constrained substances”. “We had made the equal request on the all-celebration assembly two days returned. The Centre should still announce a distinct economic package for the State within the present circumstance,” she stated.  Watch | A heritage of pandemics given that the twentieth century The history’s worst general infectious sickness outbreak of the Spanish flu passed off in 1918. The influenza virus H1N1 killed more than 50 million people and infected over 500 million americans internationally.   6.20 p.m. | Bhopal Journalist who attended Kamal Nath’s press meet exams COVID-19 positive Panic gripped officers and journalists in Bhopal on Wednesday as a senior journalist, who had attended a press conference of former Chief Minister Kamal Nath and visited the Vidhan Sabha and the Raj Bhavan, tested fantastic for COVID-19. The journalist is the daddy of the lady, who became the primary case within the metropolis to check tremendous on March 22 after getting back from London. he is the fifteenth effective case in the State.   6.05 p.m. | New Delhi Please abide through conditions of lockdown given by PM Modi: Kejriwal Delhi CM Arvind Kejriwal addresses the media. "I enchantment to you with folded hands: please abide via the situations of lockdown announced by way of the prime minister," he says a day after Narendar Modi’s tackle to the nation announcing the nationawide 21-day lockown. "we have devised a technique to assist these private employees who will not have identification playing cards — even if they’re employed at Govt. hospitals or facilities associated with primary services or private ones — every thing to do with their manufacturing, storage or distribution will get passes. "just call 1031 and you may be assisted with guidance about the way to get an e-circulate." "This became for those associated with elementary functions; when it involves those that don’t seem to be associated with these services, there isn’t any move crucial. you can walk to your neighbourhood keep and purchase what you should, no person will stop you from doing so." He talked in regards to the considerations of clinical staff being confused through landlords. "we can take very strict motion in opposition t those landlords who’re harassing or misbehaving with medical doctors, nurses, medical institution team of workers dealing with corona sufferers based mostly most effective on suspicion; orders to this impact were issued," Mr Kejriwal stated. "I appeal to you again, the Navratras are additionally on, take a pledge that you’re going to make sure that any individual round you’re going to now not go to sleep hungry. here’s actual worship, here is actual carrier for the nation."   5.50 pm | J&okay 4 americans test high quality Kashmir 4 greater individuals testes fantastic in Kashmir on Wednesday, taking the overall number of situations to 11. All four people have been a part of a non secular event attended via a affected person who verified postive on Tuesday, talked about the Jammu & Kashmir govt. 5.30 pm | New Delhi PM Modi announces WhatsApp quantity to function coronavirus helpdesk best Minister Narendra Modi has spoke of he became very pained by the misbehaviour of some americans towards docs, airways crew and workforce of simple features who are at the forefront of combating coronavirus. He also asserted that the lethal virus doesn’t differentiate between the rich and the bad requested individuals to be at domestic and apply social distancing. Addressing people of his parliamentary constituency of Varanasi by way of video, he talked about the Mahabharata struggle turned into gained in 18 days but this conflict in opposition t coronavirus will take 21 days. He become relating to the 21 day nation-broad lockdown introduced by him on March 24. He stated that around one lakh individuals infected with COVID-19 are recuperating and this additionally has to be highlighted. The PM announced that the Centre has tied up with WhatsApp to create a helpdesk for featuring credible counsel on coronavirus. The quantity is 9013151515. 5.00 p.m.| New Delhi shops selling essentials, medicines will continue to be open all the way through 21-day lockdown: Javadekar Union minister Prakash Javadekar on Wednesday noted there turned into no want for individuals to panic as retail outlets selling necessities and drugs will continue to be open all over the 21-day lockdown imposed to combat the coronavirus outbreak. He additionally said there have been ample legal provisions obtainable to take care of black marketeers and hoarders. four.forty pm | Chennai 4.30 pm | Mumbai Passenger train capabilities cancelled till April 14 The Railways in an professional unencumber stated all passenger coach functions, including suburban trains and Kolkata Metro, will stay suspended until April 14. despite the fact, freight operations shall continue. 4.20 pm | New Delhi Delhi allows for creation of ethanol-based mostly sanitisers The Delhi govt has granted permission to all of the producers of medication and cosmetics in the capital to supply such items with ethanol because the base as much as June 30, authorities observed on Wednesday. health Minister Satyendar Jain, in a tweet, shared a replica of a round in regards to the choice taken through the Drug control branch of the Kejriwal government, and also stated, “No separate license is required for the same.” four.00 pm | London Britain’s Prince Charles tests tremendous Prince Charles, the heir to the British throne, has established advantageous for COVID-19, pronounced ITV. “The Prince of Wales has tested positive for Coronavirus,” Clarence apartment stated in a press release. “He has been exhibiting light signs however in any other case continues to be in decent fitness and has been working from domestic right through the remaining few days as common.”  The observation brought that the Duchess of Cornwall has additionally been proven but does not have the virus. The Prince and his spouse, Camilla, are self-separating at home in Scotland. “It is not viable to confirm from whom the Prince caught the virus due to the high variety of engagements he conducted in his public role throughout contemporary weeks," the statement noted. 3.50 pm | New Delhi Centre postpones Census, NPR pastime the primary part of the Census 2021 and updation of NPR, which became to begin on various dates determined with the aid of the State/UT governments beginning from April 1, 2020 and various linked box actions, are postponed until additional orders, the Ministry of domestic Affairs referred to in a press observation. Coronavirus outbreak | Census-NPR postponed till additional orders three.forty pm | Mumbai Police in Mumbai, Delhi attain out to e-commerce platforms Amidst expanding confusion over the terms and stipulations of the nationwide lockdown announced by way of best Minister Narendra Modi, the Mumbai Police on Wednesday began achieving out to e-commerce platforms to ensure that primary commodities have been brought to citizens with none hitches. meanwhile, the Delhi police have created a WhatsApp group with all e-commerce agencies to resolve concerns related to mobility on the earliest. Curfew passes could be issued to automobiles concerned in beginning of essential objects. 3.40 pm | New Delhi ECI makes it possible for use of indelible ink to mark these beneath domestic quarantine The Election fee of India allowed the use of indelible ink to mark those ordered to quarantine at home and told the fitness Ministry no longer to mark any finger on the left hand and to standardise the mark. three.30 pm | Jammu & Kashmir J&ok administration orders closure of govt workplaces The Jammu and Kashmir administration has ordered the closure of all govt places of work, excluding those offering fundamental services, till April 14 in the Union Territory. – PTI three.30 pm | New Delhi it’s no longer actual that birth has stopped everywhere, says Union Minister Prakash Javadekar, in reply to a question about grocery beginning functions suspending operations, at the cupboard briefing. 3.20 pm | Gujarat Gujarat to deliver free grocery necessities to 60 lakh ration card holders The Gujarat executive will give meals gadgets like wheat, rice, pulses and sugar freed from can charge to round 60 lakh ration card protecting families through reasonable expense stores beginning April 1, Chief Minister Vijay Rupani observed on Wednesday. 3.00 pm | New Delhi Will give the States all the ration for three months in boost: Javadekar Union Minister Prakash Javadekar, while addressing a cabinet briefing, says: "All basic goods retail outlets will remain open. but we deserve to comply with social distancing like a shopkeeper did in Anand in Gujarat or in Puducherry." He holds up photos of americans standing in circles drawn in chalk outside grocery shops. Mr. Javadekar says: "The query of what is going to ensue to the negative is raised. however we should still no longer forget that the central govt offers 80 crore people ration. it be the area’s greatest meals safety scheme," adding, "we are able to supply the states all the ration for three months in enhance." The Union Minister noted the govt offers wheat for Rs. 2 when it charges the food organization of India Rs.27, and rice for Rs.3 when it fees Rs.37. additionally study: Coronavirus | cabinet nod for provide of two kg added subsidised foodgrains via ration stores All States were informed to start helplines and the Union home Ministry will announce its own helpline quantity nowadays, says Mr. Javadekar. americans do not deserve to rush and purchase in bulk. retail outlets will stay open for 21 days, he says. "The executive is preserving an eye on the condition. in the event that they had been working here, they must had been dwelling someplace. They should live the place they are," he says when asked about migrant worker’s who’re staying at bus shelters or instruct stations. 3.00 pm | New Delhi No new case in Delhi on account that Sunday, say officials No new case of COVID-19 in Delhi has been mentioned in the past 60 hours, in accordance with Delhi executive officials. The ultimate wonderful case within the metropolis become detected on Sunday, when the entire variety of cases accelerated to 30 from 27. the whole number of circumstances has remained at 30 considering then. 2.50 pm | Tamil Nadu Tamil Nadu stories 5 new cases 5 news situations of COVID-19 had been recorded in Tamil Nadu as 4 Indonesian nationals and their commute book from Chennai confirmed advantageous at the Salem medical faculty. that they had been under quarantine on the grounds that March 22. in the meantime, Chief Minister Edappadi ok. Palaniswami noted all college students between class 1 and 9 might be declared to have handed their annual examinations for this tutorial year. the entire type 12 college students, who couldn’t seem of their public exam on March 24 would be capable of seem for the paper another day, the date for which could be declared later. 2.forty five pm | Chennai Migrant worker’s stranded as trains stop plying Migrant employees living in Chennai have been stranded at the MGR important Railway Station, after trains stopped plying on March 23. they have got been lodged at a community corridor in Chinthadripet in Chennai on account that then. The Chennai employer together with its community of volunteers is presenting meals to these worker’s. 2.20 pm | Madhya Pradesh 2nd wonderful case in Bhopal the daddy of the first affected person in Bhopal has verified positive for COVID-19, talked about Bhopal Collector Tarun Kumar Pithode. With this, two cases had been detected within the metropolis to date. also read: anxiousness grips Bhopal fuel tragedy survivors as clinic specified as COVID-19 facility 2.00 pm | Karnataka Udupi studies first COVID-19 case A 34-12 months-historic man has tested high-quality for COVID-19 right here. here’s the primary case in Udupi district. a press release issued via the District fitness and family Welfare Officer right here on Wednesday noted that the man had come from Dubai to Udupi district on March 18. when you consider that he showed indicators of COVID-19, he became admitted to the District government health center here on March 23. His throat swab turned into despatched for check and the preliminary report mentioned that he had demonstrated superb for COVID-19. seventy five-12 months-old woman who verified advantageous for COVID-19 dies in Karnataka 1.forty five pm | New Delhi PM Modi chairs cupboard assembly sans the oval table The colossal oval desk changed into gone and leading Minister Narendra Modi and other ministers sat in chairs stored at a distance from each and every other as they practised “social distancing” to combat COVID-19 right through a cupboard meeting on Wednesday. pictures confirmed that the ministers had small aspect tables subsequent to their chairs to permit them to preserve their files. 1.30 pm | Karnataka COVID-19 patient dies in Karnataka A seventy five-yr-old girl from Gauribidanur in Chikkaballapur district, who had tested high-quality for COVID-19 after getting back from Mecca, died in the wee hours of Wednesday at the State-run Bowring and woman Curzon hospital in Bengaluru. fitness and family unit Welfare Minister B. Sriramulu proven this in a tweet. “The effective patient had a few co-morbidities including diabetes and cardiac concerns. She has also suffered a hip fracture and changed into present process remedy for a similar. The explanation for her dying should be conventional simplest after all her different experiences are out,” Mr Sriramulu tweeted. the first COVID-19-related loss of life in Karnataka was pronounced from Kalaburagi. A 76-year-old man, additionally with a go back and forth historical past Mecca, had died on March 12. He became the nation’s first victim of COVID-19. 1.25 pm | Rajasthan Rajasthan reports four new situations 4 new COVID-19 superb instances were mentioned in Rajasthan, of which three are from Bhilwara and one from Jodhpur. the total number of instances in Rajasthan is now 36. among the Bhilwara cases, two of the infected are hospital body of workers. The different one became infected with the aid of a doctor who changed into confirmed fantastic just a few days ago. The Jodhpur patient is a coach co-traveller of two who had demonstrated fantastic for COVID-19 past. 1.20 pm | country U.S. Senate, White apartment agree on $2 trillion Coronavirus rescue plan The White condo and Senate leaders of each parties announced agreement early Wednesday on remarkable emergency legislations to rush sweeping help to groups, employees and a fitness care system slammed by way of the coronavirus pandemic. The urgently necessary pandemic response measure is the biggest financial rescue measure in history and is supposed as a weeks- or months-lengthy patch for an economic system spiraling into recession and a nation dealing with a potentially ghastly toll.   1.10 pm | Mizoram Mizoram man who again from Netherlands is 2d high quality case in Northeast A 50-12 months-historic man from Mizoram who again from the Netherlands on March 16 has confirmed tremendous for COVID-19, State’s health Minister R. Lalthangliana said on Wednesday. His is the 2d case in the Northeast. the first was that of a 23-yr-ancient biomedicine student who had again to her native land Imphal, Manipur’s capital, from the U.k. on March 21.   1.05 pm | Kerala Kerala enforces total prohibition The Kerala executive on March 25 enforced total prohibition in the State to prevent americans from queuing up in front of State-run liquor shops right through the COVID-19 outbreak.   however, it is weighing a thought to enable the Kerala State drinks organisation or shuttered bars to sell liquor online or as takeaway. currently, it is unlawful for bars to permit consumers to remove alcohol. therefore, the government will have to tweak the liquor guidelines to approve the proposed transaction.   1 pm | Gujarat total situations in Gujarat jump to 38 the overall number of COVID-19 demonstrated cases in Gujarat touched 38 on Wednesday after five new cases have been said during the past 24 hours. This contains three instances of native transmission. Gujarat’s main Secretary (health) talked about during the morning briefing thata complete of 20,688 people are under quarantine in the State. Of this, 430 people are under govt quarantine facility, 38 at private amenities, and 20,220 are below domestic quarantine throughout Gujarat. The district-sensible spoil-up of the situations are as follows: Ahmedabad – 14; Surat – 7; Rajkot – three; Vadodara – 7; Gandhinagar – 6; Kutch – 1 12.50 pm | Maharashtra we are able to rejoice Gudi Padwa as soon as we defeat this virus: Uddhav Thackeray Maharashtra Chief Minister Uddhav Thackeray, in a press conference in Mumbai, urged the residents to dwell indoors. "i’m not here to claim anything terrible today. i know what you have been via remaining night," he pointed out, including that we do not know the place the "enemy" is. "may be this lockdown is bringing families together… it be some thing we misplaced through the years," he stated.   He mentioned that the government is in talks with the corporates in regards to the plight of day by day wage labourers, and advised that payments to employees no longer be stopped. Please go by myself if you are going to get greens, medicines, he informed the citizens. "these days is Gudi Padwa (Maharashtrian ). Ideally it would have been festive temper. we’re going to have a good time it, however only after defeating this virus," talked about Mr. Thackeray. 12.forty pm | Kerala Kerala to deliver free ration to all The Kerala government on Wednesday determined to supply free provisions to all ration card holders in the State. below poverty line cardholders will get an additional 35 kg of rice free subsequent month. different sections of cardholders, including above the poverty line and those maintaining non-precedence playing cards would get up to fifteen kg of rice free. The govt would also provide free provision kits to those below home quarantine, no matter their revenue reputation.   12.30 pm | Chennai Police register instances in opposition t three for leaping home quarantine The police have registered situations in opposition t three greater grownup who left their buildings regardless of being on domestic quarantine. On Tuesday, within the first such case, Kodambakkam police had registered a case against a forty five-year-ancient civil engineer for leaving his home, violating domestic quarantine. The police have registered cases beneath sections of 188 (disobedience to order duly promulgated by public servant), 269 (negligent act more likely to unfold infection of disease dangerous to lifestyles), area 270 (malignant act more likely to unfold an infection of ailment bad to life), part 271 (disobedience to quarantine rule) and section three of the Epidemic diseases Act and Sec 51(b) of the disaster administration Act.   12.20 pm | Maharashtra 5 extra instances detected in western Maharashtra Maharashtra’s ‘sugar heartland’ witnessed a surge in COVID-19 cases after 5 participants of a household in Sangli district in the western a part of the State validated fine, talked about authorities on Wednesday. The State’s tally of positive circumstances rose to 112. while particulars are awaited, it’s believed that the members of this family from Sangli’s Islampur tehsil either themselves had a background of shuttle to West Asia or had been shut contacts of in the past diagnosed instances. 12.10 pm | Tamil Nadu Tamil Nadu sanctions ₹2,187 crore towards money aid, basic commodities The Tamil Nadu executive has sanctioned funds to the tune of ₹2,187.8 crore, in opposition t imposing the announcement made by using Tamil Nadu Chief Minister Edappadi okay. Palaniswami within the State Legislative assembly that cash guide of ₹1,000 and basic commodities can be dispensed to every of the eligible ration card holders across the State, as a part of measures to mitigate the impact of the shut down on account of COVID-19. in keeping with a government order issued few hours after the CM’s announcement in the condo on Tuesday, ₹2,014.69 crore has been earmarked towards distributing cash information and ₹173.1 crore has been allotted for presenting simple commodities through Public Distribution device (PDS) stores.   12 pm | Delhi No need of panic-purchasing: Arvind Kejriwal Lieutenant Governor of Delhi Anil Baijal and Chief Minister Arvind Kejriwal on Wednesday certain Delhiites that the supply of elementary items should be ensured. "Given the situation we are in, there changed into no wrong way apart from a lockdown. We additionally desire minimal inconvenience to the public, and may make sure the availability of standard items," pointed out Mr. Baijal. "Milk, vegetables, edibles, products of every day use, and drug treatments are basic objects, and we can be sure their availability. The Centre, LG and that i are all working together. I are looking to guarantee you that there isn’t any need to have interaction in panic-purchasing. all of your wants can be met, I assure you, spoke of Mr. Kejriwal. He brought that the government is making arrangements to challenge passes, and that through Wednesday evening, preparations should be in vicinity to subject e-passes for those engaged in the supply of primary items. this will encompass vegetable providers, pointed out the Delhi CM.   11.50 am | Nagaland Village councils proscribing entry of americans in Nagaland Sreets in the Nagaland were empty on Wednesday on the first day of nationwide lockdown imposed through prime Minister Narendra Modi in an try and prevent the spread of the coronavirus. Police personnel together with ‘Dobashis’ have been deployed in strategic areas in the districts to avert move of individuals, except people who are outdoors for paying for standard commodities and drugs. within the state capital, volunteers of Angami adolescence agency had been additionally manning critical points to prevent people from stepping outide their homes. Many village councils have issued strict orders restricting the entry of people into the villages, and restraining the locals from leaving the area, with out the permission of the authorities worried. – PTI eleven.40 am | Manipur No newspapers in Manipur, new 12 months celebrations lacklustre The individuals in Manipur aroused from sleep on Wednesday morning to discover that there have been no newspapers, certainly when individuals want tips following the report that a 23-yr-ancient woman turned into the first person to have gotten smaller COVID-19 in the Northeast location. This despite the Ministry of suggestions and Broadcasting, in a March 23 legitimate letter, instructing all Chief Secretaries to ensure the operational continuity of digital and print media within the face of the pandemic.     11.30 am | Kerala The lockdown will repay, says Alappuzha survivor He had his first tryst with a lockdown in the chinese language city of Wuhan, floor zero of the COVID-19 outbreak. After receiving a text message in the early hours of January 23, he, together with his pals, scrambled to attain the Wuhan Tianhe foreign airport to trap a flight again home. With the lockdown already in place, the airport turned into closed by the time they reached there. but the community become fortunate satisfactory to get into the remaining coach heading to Kunming, some 1,800 km away. From there, they all boarded a flight first to Kolkata and landed in Kochi on January 24. After attaining his apartment in Alappuzha, the 23-12 months-historical medical student went straight into strict self-quarantine. The relaxation are ordinary facts. He changed into established superb for COVID-19 on February 2, the 2d such case within the country. but, in two weeks, the clinical scholar grew to be the first grownup in India to be cured of the ailment.   eleven.25 am | Bihar Bihar studies fourth COVID-19 case A 39-12 months-old man from Patna who these days returned from Gujarat has been confirmed effective for COVID-19 in Bihar. He has been admitted to the isolation ward of government-owned Nalanda scientific school and medical institution in Patna, mentioned nodal officer for COVID-19 in Bihar, Dr. Ragini Mishra. eleven.20 am Practising social distancing…     eleven.10 am | Jodhpur 277 individuals evacuated from coronavirus-hit Iran reach military facility in Jodhpur A batch of 277 americans evacuated from the coronavirus-hit Iran arrived at the Jodhpur airport in Rajasthan on Wednesday early morning, a defence spokesperson observed. He talked about preliminary screening of the evacuees, primarily pilgrims, became carried out at the airport upon arrival and thereafter they had been taken to the army wellness Facility deploy on the Jodhpur militia Station.   11 am |  Kerala life at an apartment advanced during lockdown With 1,268 flats cut up into 15 blocks and unfold over 26 acres, the DLF New city Heights at Kakkanad is conveniently probably the most greatest condominium complexes now not simply in Kochi however in the total State. The problem of managing a prolonged lockdown, therefore, is big with the residents’ welfare affiliation giving excellent precedence to waste administration. “Many residents have gone to their hometowns while there are a huge variety of retirees who’re staying back. we now have drawn up huge plans to make their live clean and comfortable with no need to undertaking out for the rest,” mentioned S. Anish, secretary of the association.   10.30 am | Delhi Delhi loss of life not due to COVID-19, says fitness Minister The Delhi loss of life suggested on Tuesday nighttime has verified poor for COVID-19, pointed out the Union health Minister in a unencumber issued on Wednesday morning. The death toll as a result of COVID-19 in India is now 9. 10.20 am | India Flipkart suspends operations Walmart-owned Flipkart on Wednesday stated it become suspending its operations temporarily as India entered right into a 21-day lockdown to include the spread of COVID-19 pandemic. “Consequent to the order issued on March 24 by means of the Ministry of home Affairs announcing a 21-day lockdown across India to include the unfold of the unconventional coronavirus causing Covid-19, we’re quickly suspending our services,” Flipkart spoke of in a blogpost. The blog additional referred to “we can be returned to serve you as quickly as viable.”   10.10 am | Madhya Pradesh five in Indore examine fine, MP cases rise to 14 five humans admitted in different hospitals of Indore have demonstrated wonderful for coronavirus taking the variety of COVID-19 cases in Madhya Pradesh to 14, fitness officials spoke of on March 25. none of the sufferers in Indore have background of go back and forth to abroad.     9.fifty five am | New Delhi The Ministry of domestic Affairs has asked deepest safety organizations to no longer lay off security guards as malls, retail outlets and different organisations are shut. "this is the time for the deepest safety industry to adopt a humane approach and give protection to its group of workers and contributors from lay-offs," it said in an order. 9.30 am | Delhi What lockdown? despite repeated appeals from the prime Minister Narendra Modi and Delhi Chief Minister Arvind Kejriwal to the general public on the perils of gathering in a crowd all through the COVID-19 pandemic, food markets in West Delhi noticed robusts crowds on day 1 of the 21-day national lockdown.   9.20 am | New Delhi No scarcity of elementary gadgets, reiterates Centre The Ministry of home Affairs on Wednesday free up a GO reiterating that there will be no scarcity of essential objects all over the 21-day lockdown. It asked the States to publicise that meals, drugs, civil elements and primary items may be available, amid percentages of "rumour mongering" that there is a shortage. eight.30 am | New Delhi   Govt offers vigor to zonal DCs to take strict action towards landlords evicting doctors The executive on Wednesday gave vigour to zonal Deputy Commissioners to take “strict penal action” towards landlords who were forcing docs and paramedical body of workers, engaged in fighting COVID-19, to vacate their rented premises. in keeping with a government notification, such behaviour “no longer only strikes on the root of the fight towards the COVID-19 pandemic but additionally tantamount to obstruction of obligation of essential services”. four.30 am | Jodhpur 277 Indians lower back from Iran via Mahan air All 277 passengers who lower back from Iran and established COVID-19 bad were sent to be quarantined at Jodhpur’s army quarantine facility. They flew early morning by way of two particular Air India flights at 3.30 a.m. and four.30 a.m. from Delhi to Jodhpur within the last domestic flights earlier than lock down. the first flight was commanded by way of Capt M.S. Zaheer and Co-pilot Tulunga and second flight commanded by using Capt.  Radheyshyam Arora and Co-pilot G. Singh. 3.30 am | New Delhi   Govt bans export of anti-malarial drug hydroxycloroquine Amid the coronavirus outbreak, the executive on Wednesday banned export of anti-malarial drug hydroxycloroquine, with immediate impact to be certain adequate availability of the medication within the domestic market. Indian Council of medical analysis (ICMR) Director everyday Balram Bhargava had on Monday recommended the use of hydroxychloroquine for treating healthcare laborers dealing with suspected or demonstrated coronavirus situations and also the asymptomatic family unit contacts of the lab-verified situations.   2.00 am | Chennai TN records first dying of COVID-19 affected person Tamil Nadu recorded its first demise of a patient, who had established fine for coronavirus disorder (COVID-19). The fifty four-yr-old man, who confirmed nice on March 23 and changed into undergoing remedy at government Rajaji health center, Madurai, died. At 2:02 a.m. on Wednesday, fitness Minister C. Vijayabaskar tweeted, "regardless of our most useful efforts, the COVID-19 fantastic patient in Madurai Rajaji sanatorium passed away a few minutes returned. He had scientific history of prolonged illness with steroid based continual Obstructive Pulmonary Diseas, uncontrolled diabetes with hypertension."  Railways exploring manufacture of clinical gadgets The Indian Railways is exploring the probability of producing choose primary clinical items comparable to sanatorium beds, clinical trolleys and sanitizers at its a considerable number of creation gadgets. In a communication to ordinary managers at its production devices, the Railway Board on Tuesday asked them to “assess the feasibility to manufacture these objects in enormous quantities [as may be required] at brief note. gadgets identified consequently could be communicated to the Board along with its likely production rate.” records | How organized are India’s States in fitness infrastructure to tackle COVID-19 The chart plots the variety of COVID-19 pattern checking out centres towards the common number of americans served via one checking out centre throughout States. whereas Maharashtra has the highest number of testing centres and comparatively enhanced coverage, the State is still under-fitted to detect cases as one testing centre is available for 1.02 crore people.   (With inputs from PTI)   army sets up helplines throughout J&okay, Ladakh As a part of its effort to generate consciousness among the many americans about coronavirus, military’s Northern Command on March 24 based a few telephone helplines across the Union Territories of Jammu and Kashmir and Ladakh, a defence spokesman spoke of. whereas Srinagar residents can reach out for aid on 0194-2467326, the residents of alternative districts can are seeking suggestions through helplines at Baramulla (0195-2238826), Kupwara (0195-5252996), Shalateng (0194-2496618), Awantipura (0193-3247087), Nagrota (0191 254 7896), Akhnoor (0192 425 4244), Rajouri (0196 226 2477), Batote (0199 824 4361), Palma (0196 226 1503), Reasi (0199 124 5319) and Narian (0196 023 0026). The helpline numbers for the UT of Ladakh are Leh (01982- 259011), Karu (01982- 249078), Kumbathang (01935- 278113) and Partapur(01980- 221013), he said. Coronavirus | army’s northern command sets up distinctive COVID-19 helplines in J&ok, Ladakh Biocept, Inc. (BIOC) CEO Michael Nall on this fall 2019 outcomes – income name Transcript To make sure this doesn’t occur in the future, please permit Javascript and cookies on your browser.is this going on to you often? Please record it on our feedback forum. you probably have an advert-blocker enabled you can be blocked from continuing. Please disable your ad-blocker and refresh. Reference identification: Tonix prescribed drugs reviews Fourth Quarter and whole yr 2019 economic consequences and Operational Highlights advantage Vaccine, TNX-1800 in construction to offer protection to towards New Coronavirus disease 2019 (COVID-19) based on the business’s Horsepox Virus Vaccine Platform knowledge Vaccine, TNX-801 in construction to protect in opposition t Smallpox and Monkeypox in keeping with Horsepox Virus intervening time analysis results for part 3 aid analyze of TNX-102 SL for the management of Fibromyalgia anticipated Third Quarter 2020; Topline facts expected First Half 2021 improved Pipeline in 2019 with Three In-licensed classes First Quarter 2020 inventory offerings Raised $29.0 Million in net Proceeds to support Pipeline development new york, March 24, 2020 (GLOBE NEWSWIRE) — Tonix prescribed drugs conserving Corp. (TNXP) (Tonix or the company), a scientific-stage biopharmaceutical enterprise, these days announced monetary results for the quarter and 12 months ended December 31, 2019, and supplied an outline of fresh operational highlights. “Our focal point in 2020 might be on additional advancement of our vaccine and ache classes: TNX-1800 as a possible vaccine to give protection to in opposition t COVID-19, TNX-801 as a potential vaccine against smallpox and monkeypox, and TNX-102 SL for the management of fibromyalgia.  We predict outcomes of the meantime analysis for the part three aid analyze for TNX-102 SL for the medication of fibromyalgia within the third quarter of this yr, however interruptions as a result of the COVID-19 pandemic can also alter these timelines,” observed Seth Lederman, M.D., President and Chief govt Officer.  “in addition to these courses, we preserve a powerful and transforming into pipeline of product candidates together with TNX-102 SL as a medicine for agitation in Alzheimer’s ailment and alcohol use disorder, TNX-601 CR as a medication for foremost depressive disorder, medication for PTSD and medication for corticosteroid-induced cognitive dysfunction, TNX-1300 for the remedy of cocaine intoxication, TNX-1500 for the prevention and remedy of organ transplant rejection, and TNX-1200 as a vaccine against smallpox and monkeypox ailment.  additionally, we appear forward to advancing our pipeline of other product candidates.” Story continues contemporary Highlights research and building TNX-1800 (are living recombinant horsepox virus (rHPXV/SARS-CoV2-S3) vaccine from mobile tradition) In first quarter 2020, Tonix introduced a strategic collaboration with the Southern research Institute to help construction of TNX-1800, a potential vaccine to offer protection to in opposition t COVID-19.  TNX-1800 is in keeping with Tonix’s proprietary horsepox vaccine platform, which the business believes may also be engineered to specific relevant protein antigens from diverse infectious diseases to make a variety of vaccines.  The collaboration with Southern research will boost and look at various TNX-1800, which is designed to specific the Spike protein from the SARS-CoV-2 virus that explanations COVID-19.  Tonix plans to check even if vaccination of animals with TNX-1800 will elicit an immune response to the SARS-CoV-2 Spike protein and if so, whether such an immune response will give protection to animals against COVID-19-like disease.  TNX-1800 is within the pre-medical, pre-Investigational New Drug (IND) utility stage of building.  The company expects preliminary facts from animal experiments in the third quarter of 2020, however the COVID-19 pandemic may also lead to a extend during this timeline. TNX-801 (live synthesized horsepox virus (sHPXV) vaccine from mobile tradition) Tonix is constructing TNX-801 as a preventative vaccine for energetic immunization towards smallpox and monkeypox diseases for people at high risk for infection.  in the first quarter of 2020, the company introduced statistics on the American Society of Microbiology Biothreats meeting that showed that TNX-801 included macaques from problem with monkeypox virus. TNX-102 SL (cyclobenzaprine HCl sublingual pills) all through the fourth quarter of 2019, the business initiated the phase 3 aid look at, a possible pivotal analyze of TNX-102 SL* (cyclobenzaprine HCl sublingual pills) 5.6 mg, a non-opioid, centrally acting analgesic, taken every day at bedtime for the administration of fibromyalgia.  reduction is a double-blind, randomized, placebo-controlled adaptive design trial designed to evaluate the efficacy and safety of TNX-102 SL in fibromyalgia.  meantime analysis consequences are anticipated in the third quarter of 2020, with topline results anticipated in the first half of 2021 in keeping with the at present-deliberate sample size.  The COVID-19 pandemic can also lead to a lengthen in recruitment for reduction which might extend the intervening time analysis and topline outcomes, however thus far the trial is on agenda. Supported by means of the old safety and efficacy findings of TNX-102 SL in fibromyalgia at 2.8 mg and posttraumatic stress ailment (PTSD) at 5.6 mg, Tonix believes that the usage of the 5.6 mg dose of TNX-102 SL in the part 3 aid fibromyalgia analyze has the potential to provide medical facts to guide the efficacy and security of TNX-102 SL for the management of fibromyalgia.  The registration of TNX-102 SL 5.6 mg for the fibromyalgia indication is expected to be supported by the long-term protection publicity records from the PTSD software for TNX-102 SL 5.6 mg.  In February 2020, the enterprise introduced it stopped enrollment in the part 3 restoration look at of TNX-102 SL* (cyclobenzaprine HCl sublingual tablets) 5.6 mg for the remedy of PTSD following an unblinded, pre-detailed interim evaluation with the aid of the unbiased statistics Monitoring Committee (IDMC).  according to period in-between evaluation effects of the first 50% of enrolled members, the IDMC suggested stopping the trial for futility as TNX-102 SL is unlikely to exhibit a statistically big improvement within the basic endpoint of common trade from baseline within the severity of PTSD signs, as measured via the Clinician-Administered PTSD Scale for DSM-5 (CAPS-5) between those handled with TNX-102 SL and those receiving placebo.  Preliminary blinded security statistics from these participants didn’t demonstrate any serious and/or unexpected adverse movements and the choice to discontinue enrollment in the examine is not involving safeguard.  The enterprise intends to continue discovering these individuals presently enrolled unless completion and then proceed with a full evaluation of the unblinded statistics to verify the next steps in this program, with the topline results anticipated to be pronounced within the second quarter of 2020.  TNX-102 SL is in development for the remedy of agitation in Alzheimer’s ailment (AAD), which has been precise as a quick music construction application through the food and Drug Administration (FDA). The program is competent for a part 2 study which might doubtlessly function a pivotal efficacy examine to assist a new Drug software (NDA) approval. TNX-102 SL is in building as a treatment for alcohol use sickness (AUD), with an IND software to be submitted within the first half of 2020.  The AUD application is expected to be capable for a section 2 proof-of-concept study upon FDA clearance of the IND software.  AUD is a chronic relapsing mind ailment characterized via compulsive alcohol use, loss of control over alcohol consumption, and a negative emotional state when now not using. TNX-601 CR (tianeptine oxalate controlled-release) The enterprise introduced within the fourth quarter of 2019 the successful completion of a phase 1 study evaluating the security, tolerability and pharmacokinetics (PK) of managed liberate (CR) formulations of TNX-601 (tianeptine oxalate).  TNX-601 CR is being developed as a once-daily medication for principal depressive disease (depression) in addition to PTSD and corticosteroid-brought on cognitive dysfunction.  Tonix plans to delivery the primary efficacy trial ex-U.S. in 2021 and request a pre-IND assembly with the FDA in 2020. TNX-1300 (double mutant cocaine esterase) TNX-1300 is a recombinant protein under building as a medicine for a lifestyles-threatening diploma of cocaine intoxication.  TNX-1300 became granted step forward remedy designation by means of the FDA.  Tonix in-licensed TNX-1300 in might also 2019 from Columbia university, after a phase 2 look at on volunteers confirmed that TNX-1300 disintegrates cocaine within the blood circulate after i.v. cocaine challenge.  In 2019, the enterprise met with FDA to discuss and reach contract on the design of toxicology stories for TNX-1300 to aid a section 2 clinical examine.  The company has recertified TNX-1300 drug product for use in future clinical trials. TNX-1500 (monoclonal antibody anti-CD154) The company entered right into a research collaboration with Massachusetts universal medical institution to strengthen TNX-1500, Tonix’s internally developed, proprietary anti-CD154 (or CD40-ligand) monoclonal antibody that goals CD154 for the prevention and medication of organ transplant rejection.  TNX-1500 is additionally a possible medication for autoimmune conditions. different Pipeline classes TNX-1600 (triple reuptake inhibitor): obtained an exclusive license for a triple reuptake inhibitor, TNX-1600, to treat PTSD and potentially different central frightened gadget problems.  The transaction become a license agreement with Wayne State school and an asset acquisition from TRImaran Pharma, Inc. TNX-1700 (recombinant trefoil aspect 2, or rTFF2): bought an exclusive license from Columbia institution for the building of a biologic, TNX-1700 (recombinant trefoil factor 2, or rTFF2), for the medication of gastric and pancreatic cancers.  The in-licensed know-how become invented and developed, in part, through Dr. Timothy C. Wang, Chief, Division of Digestive and Liver diseases, and Director of the Gastrointestinal and Pancreas cancer software and Tumor Biology and Microenvironment software in the Herbert Irving melanoma middle at Columbia institution. financial Fourth Quarter 2019 financial outcomes research and building costs for the fourth quarter of 2019 totaled $5.7 million, compared to $5.1 million for the same duration in 2018. This raise is essentially as a result of increased work concerning TNX-601 CR, including the PK study, and an increase in non-medical fees related to pipeline building. conventional and administrative fees for the fourth quarter of 2019 totaled $3.0 million, in comparison to $2.6 million for the same length in 2018. The modest raise is primarily as a result of an increase in patent prosecution and preservation fees.   internet loss attainable to general stockholders was $eleven.2 million, or $2.86 per share, for the fourth quarter of 2019, compared to net loss of $10.9 million, or $59.eighty five per share, for the fourth quarter of 2018. The weighted typical standard shares magnificent, basic and diluted, have been 3,912,800 for the fourth quarter of 2019 and 181,344 for the fourth quarter of 2018, which quantities had been retroactively restated to reflect a 1-for-10 reverse inventory cut up of our issued and surprising shares that became effectuated on November 1, 2019. Full year 2019 economic effects research and construction expenses for full 12 months 2019 totaled $18.2 million, in comparison to $17.6 million for the same period in 2018. This boost is primarily due to the ramp-up of labor concerning TNX-601 and an increase in charges related to pipeline development. conventional and administrative costs for full year 2019 totaled $10.6 million, compared to $8.eight million for a similar duration in 2018. The increase is basically due to better insurance premiums and an increase in prison expenses.   net loss available to commonplace stockholders changed into $31.1 million, or $19.33 per share, for full 12 months 2019, compared to web lack of $29.4 million, or $259.85 per share, for full 12 months 2018. The weighted average standard shares outstanding, fundamental and diluted, for 2019 became 1,608,568 shares. The weighted general general shares fabulous, simple and diluted, for 2018 become 112,968 shares. At December 31, 2019, Tonix had $eleven.2 million of cash and cash equivalents, in comparison to $25.0 million as of December 31, 2018. within the first quarter of 2020, the business raised internet proceeds of approximately $29.0 million through equity financings and warrant workout routines. Following the offerings, the business had an mixture of forty nine,353,134 shares of normal stock incredible.  money utilized in operations was $26.7 million for the full year 2019, compared to $24.0 million for the total 12 months 2018. About TNX-801* and TNX-1800* TNX-1800 is a modified horsepox virus this is designed to specific the Spike protein of the SARS-CoV-2 virus that causes COVID-19.  TNX-801 is a reside virus vaccine in accordance with synthesized horsepox1.  Horsepox and vaccinia are intently linked orthopoxviruses which are believed to share a typical ancestor.  are living replicating orthopoxviruses, like vaccinia or horsepox, can also be engineered to specific international genes and had been explored as structures for vaccine building because they possess; (1) gigantic packaging skill for exogenous DNA inserts, (2) exact virus-specific handle of exogenous gene insert expression, (three) lack of persistence or genomic integration within the host, (4) mighty immunogenicity as a vaccine, (5) means to impulsively generate vector/insert constructs, (6) easily manufacturable at scale, and (7) capability to give direct antigen presentation. Relative to vaccinia, horsepox has appreciably diminished virulence in mice1.  TNX-801 vaccinated macaques showed no overt clinical signals after monkeypox challenge2.  1Noyce RS, et al. (2018) PLoS One. 13(1):e01884532Noyce, RS, et al. synthetic Chimeric Horsepox Virus (scHPXV) Vaccination Protects Macaques from Monkeypox* presented as a poster on the American Society of Microbiology BioThreats convention  – January 29, 2020, Arlington, VA. (https://content material.equisolve.internet/tonixpharma/media/10929ac27f4fb5f5204f5cf41d59a121.pdf ) *TNX-801 and TNX-1800 are in the pre-IND stage and haven’t been permitted for any indication about the phase three reduction study The relief look at is a double-blind, randomized, placebo-managed adaptive design trial designed to consider the efficacy and protection of TNX-102 SL (cyclobenzaprine HCl sublingual pills) in fibromyalgia. The trial is expected to sign up about 470 sufferers across about forty U.S. websites. For the first two weeks of remedy, there will be a run-in period wherein sufferers will beginning on TNX-102 SL 2.eight mg (1 tablet) or placebo. After the first two weeks, all sufferers can have the dose improved to TNX-102 SL 5.6 mg (2 x 2.eight mg drugs) or two placebo capsules for 12 weeks. The fundamental endpoint is day by day diary pain severity rating exchange from baseline to Week 14 (the usage of the weekly averages of the daily numerical rating scale ratings), analyzed via combined model repeated measures with numerous imputation. The aid analyze is expected to have one unblinded meantime evaluation when the study has consequences from approximately the first 50% of efficacy-evaluable patients, pending agreement with the FDA. further details concerning the aid analyze are available at www.theRELIEFstudy.com or clinicaltrials.gov (NCT04172831). About Tonix prescription drugs keeping Corp. Tonix is a medical-stage biopharmaceutical business concentrated on discovering, licensing, acquiring and developing drugs and biologics to treat and prevent human ailment and alleviate suffering. Tonix’s current portfolio contains biologics to steer clear of infectious diseases and small molecules and biologics to deal with pain, psychiatric and dependancy circumstances. In 2020, Tonix announced a program to increase a possible vaccine, TNX-1800* (are living modified horsepox virus vaccine for percutaneous administration) to give protection to towards the unconventional coronavirus ailment emerging in 2019, or COVID-19.  TNX-1800 is in line with Tonix’s proprietary horsepox vaccine platform and is molecularly designed to categorical the Spike protein of the SARS-CoV-2  virus that reasons COVID-19.  TNX-801* (are living horsepox virus vaccine for percutaneous administration) is in construction to protect against smallpox and monkeypox. Tonix’s most advanced drug building programs are concentrated on delivering safe and valuable lengthy-term remedies for fibromyalgia, or FM, and posttraumatic stress disorder, or PTSD. Tonix’s most advanced product candidate, TNX-102 SL**, is in part three development as a bedtime remedy for fibromyalgia and PTSD. The enterprise is enrolling individuals in the section three reduction trial in fibromyalgia and expects consequences from an unblinded meantime evaluation within the third quarter of 2020 and topline information within the first half of 2021.  The section three recovery trial (P302) for TNX-102 SL (alternate name Tonmya***) in PTSD has stopped enrollment in keeping with the independent statistics Monitoring Committee’s advice to stop the analyze for futility following an period in-between analysis of the first 50% of enrolled members. Topline statistics for recuperation are anticipated in the 2d quarter of 2020. TNX-102 SL for PTSD has U.S. food and Drug Administration (FDA) breakthrough remedy Designation.  TNX-102 SL is also in building for agitation in Alzheimer’s disease and alcohol use ailment (AUD). The agitation in Alzheimer’s sickness application is phase 2 equipped with FDA fast track designation, and the development software for AUD is in the pre-Investigational New Drug (IND) application stage. Tonix‘s programs for treating dependancy conditions additionally encompass TNX-1300* (T172R/G173Q double-mutant cocaine esterase 200 mg, i.v. solution), which is in section 2 development for the medication of cocaine intoxication and has FDA breakthrough therapy Designation. TNX-601 CR (tianeptine oxalate controlled-release pills) is in building as a daytime medicine for melancholy as well as PTSD and corticosteroid-triggered cognitive dysfunction. the primary efficacy examine in depression will be performed outdoor the U.S. TNX-1600 (a triple reuptake inhibitor) is a pre-medical new molecular entity (NCE) being developed as a medication for PTSD. Tonix’s preclinical pipeline comprises TNX-1500 (anti-CD154), a monoclonal antibody being developed to steer clear of and deal with organ transplant rejection and autoimmune conditions and TNX-1700 (rTFF2), a biologic being developed to deal with gastric and pancreatic cancers. TNX-1200* (reside vaccinia virus vaccine for percutaneous administration) is in building to give protection to in opposition t smallpox and monkeypox. ultimately, TNX-701 (undisclosed small molecule) to steer clear of radiation effects is being superior as a medical countermeasure to enhance biodefense. *TNX-1800, TNX-801, TNX-1200 and TNX-1300 are investigational new biologics and have not been accredited for any indication. **TNX-102 SL (cyclobenzaprine HCl sublingual tablets) is an investigational new drug and has no longer been authorised for any indication. ***Tonmya has been conditionally approved with the aid of the FDA because the proposed change name for TNX-102 SL for the remedy of PTSD. This press release and additional advice about Tonix will also be found at www.tonixpharma.com. forward searching Statements definite statements during this press free up are ahead-searching inside the which means of the private Securities Litigation Reform Act of 1995. These statements may be identified by the use of forward-searching phrases such as “expect,” “accept as true with,” “forecast,” “estimate,” “are expecting,” and “intend,” among others. These ahead-looking statements are in keeping with Tonix’s existing expectations and actual consequences may differ materially. There are a number of factors that may trigger specific pursuits to vary materially from these indicated via such ahead-searching statements. These elements consist of, however aren’t confined to, hazards involving failure to obtain FDA clearances or approvals and noncompliance with FDA laws; delays and uncertainties brought about through the world COVID-19 pandemic; dangers regarding the timing and progress of clinical construction of our product candidates; our want for further financing; uncertainties of patent insurance plan and litigation; uncertainties of govt or third celebration payor repayment; limited research and development efforts and dependence upon third parties; and large competitors. as with any pharmaceutical beneath development, there are significant dangers within the building, regulatory approval and commercialization of latest products. Tonix doesn’t undertake an obligation to update or revise any ahead-looking remark. investors may still read the chance elements set forth within the Annual report on form 10-k for the yr ended December 31, 2019, as filed with the Securities and trade fee (the “SEC”) on March 24, 2020, and periodic experiences filed with the SEC on or after the date thereof. All of Tonix’s forward-searching statements are expressly qualified by all such chance elements and different cautionary statements. The guidance set forth herein speaks handiest as of the date thereof. Tonix prescription drugs reports Fourth Quarter 2019 monetary outcomes TONIX prescription drugs holding CORP. CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (in heaps, except share and per share quantities) (Unaudited) Three Months Ended December 31, yr Ended December 31,   2019 2018 2019 2018 expenses and expenses analysis and building $ 5,690 $ 5,057 $ 18,192 $ 17,558 normal and administrative 3,044 2,593 10,636 eight,764 complete costs and charges eight,734 7,650 28,828 26,322 working loss (eight,734) (7,650) (28,828) (26,322) pastime income, net 27 62 210 233 internet loss $ (eight,707) $ (7,588) $ (28,618) $ (26,089) favourite stock deemed dividend 2,474 three,266 2,474 3,266 internet loss attainable to ordinary stockholders $ (eleven,181) $ (10,854) $ (31,092) $ (29,355) web loss per ordinary share, primary and diluted $ (2.86) $ (fifty nine.eighty five) $ (19.33) $ (259.eighty five) Weighted regular typical shares spectacular, primary and diluted* 3,912,800 181,344 1,608,568 112,968 * All per share amounts and number of shares within the condensed consolidated financial statements were retroactively restated to reflect a 1-for-10 reverse inventory split. TONIX prescription drugs keeping CORP. CONDENSED CONSOLIDATED stability SHEETS (in thousands) (Unaudited) (1)   December 31, 2019 December 31, 2018 assets cash and money equivalents  $   eleven,249 $   25,034 prepaid costs and other   2,699   1,022 complete current property   13,948   26,056 different non-present belongings   610   263 total assets $   14,558 $   26,319 Liabilities and stockholders’ fairness total liabilities $     5,141 $     2,655 Stockholders’ fairness   9,417   23,664 total liabilities and stockholders’ fairness $   14,558 $   26,319 (1) The condensed consolidated stability sheet for the year ended December 31, 2019 and 2018 has been derived from the audited monetary statements however does not include all the suggestions and footnotes required through accounting ideas often accredited in the u.s. for complete economic statements. Bradley Saenger (corporate)Tonix Pharmaceuticalsinvestor.members of the family@tonixpharma.com(212) 980-9155 Travis Kruse (media)Russo Partnerstravis.kruse@russopartnersllc.com (212) 845-4272 Peter Vozzo (buyers)Westwickepeter.vozzo@westwicke.com (443) 213-0505  .
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